-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, G/ExoonsYm4otAUBWV8q72xd/mV7oR6/hmtvO6gxXXZ1IjtntuWO9WtsDuEcJmBa SZ0wE/sV2COw0r9P6ylf7Q== 0000922423-99-001056.txt : 19990831 0000922423-99-001056.hdr.sgml : 19990831 ACCESSION NUMBER: 0000922423-99-001056 CONFORMED SUBMISSION TYPE: SC 13D/A PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 19990830 SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: CYPRESS BIOSCIENCE INC CENTRAL INDEX KEY: 0000716054 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 222389839 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D/A SEC ACT: SEC FILE NUMBER: 005-35589 FILM NUMBER: 99701974 BUSINESS ADDRESS: STREET 1: 4350 EXECUTIVE DRIVE,SUITE 325 CITY: SAN DIEGO STATE: CA ZIP: 92121 BUSINESS PHONE: 2062989400 MAIL ADDRESS: STREET 1: 401 QUEEN ANNE AVE NORTH CITY: SEATTLE STATE: WA ZIP: 98109 FORMER COMPANY: FORMER CONFORMED NAME: IMRE CORP DATE OF NAME CHANGE: 19920703 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: ARIES FINANCIAL SERVICES INC CENTRAL INDEX KEY: 0001007000 STANDARD INDUSTRIAL CLASSIFICATION: [] FILING VALUES: FORM TYPE: SC 13D/A BUSINESS ADDRESS: STREET 1: 375 PARK AVENUE STREET 2: SUITE 1501 CITY: NEW YORK STATE: NY ZIP: 10152 BUSINESS PHONE: 2128324379 SC 13D/A 1 SCHEDULE 13D AMENDMENT NO.4 SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13D (Amendment No.4) Under the Securities Exchange Act of 1934 Cypress Bioscience, Inc. (Name of Issuer) Common Stock, par value $.02 per share (Title of Class of Securities) 2 232674 101 (CUSIP Number) Paramount Capital Asset Management, Inc. c/o Lindsay A. Rosenwald, M.D. 787 Seventh Avenue New York, NY 10019 (212) 554-4300 with a copy to: Monica C. Lord, Esq. Kramer Levin Naftalis and Frankel 919 3rd Avenue New York, NY 10021 (212) 715-9100 (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications) July 11, 1999 (Date of Event which Requires Filing of this Statement) If the filing person has previously filed a statement on Schedule 13G to report the acquisition which is the subject of this Schedule 13D, and is filing this Schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g) check the following: [ ] - -------------------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Paramount Capital Asset Management, Inc. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [ ] (b) [ ] - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* OO (see Item 3 below) - -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e) [ ] - -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------------------------------------------- NUMBER OF 7 SOLE VOTING POWER SHARES None BENEFICIALLY -------------------------------------- OWNED BY 8 SHARED VOTING POWER EACH 13,027,893 REPORTING -------------------------------------- PERSON 9 SOLE DISPOSITIVE POWER WITH None -------------------------------------- 10 SHARED DISPOSITIVE POWER 13,027,893 - -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 13,027,893 - -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES* [ ] - -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 28.3% - -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* CO - -------------------------------------------------------------------------------- - -------------------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Aries Domestic Fund, L.P. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [ ] (b) [ ] - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* OO (see Item 3 below) - -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e) [ ] - -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------------------------------------------- NUMBER OF 7 SOLE VOTING POWER SHARES None BENEFICIALLY -------------------------------------- OWNED BY 8 SHARED VOTING POWER EACH 3,855,371 REPORTING -------------------------------------- PERSON 9 SOLE DISPOSITIVE POWER WITH None -------------------------------------- 10 SHARED DISPOSITIVE POWER 3,855,371 - -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 3,855,371 - -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES* [ ] - -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 8.4% - -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* PN - -------------------------------------------------------------------------------- - -------------------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON The Aries Master Fund - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [ ] (b) [ ] - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* OO (see Item 3 below) - -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e) - -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------------------------------------------- NUMBER OF 7 SOLE VOTING POWER SHARES None BENEFICIALLY -------------------------------------- OWNED BY 8 SHARED VOTING POWER EACH 8,974,664 REPORTING -------------------------------------- PERSON 9 SOLE DISPOSITIVE POWER WITH None -------------------------------------- 10 SHARED DISPOSITIVE POWER 8,974,664 - -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 8,974,664 - -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES* [ ] - -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 19.5% - -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* CO - -------------------------------------------------------------------------------- - -------------------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Lindsay A. Rosenwald, M.D. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [ ] (b) [ ] - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* OO (see Item 3 below) - -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e) [ ] - -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OF ORGANIZATION United States - -------------------------------------------------------------------------------- NUMBER OF 7 SOLE VOTING POWER SHARES None BENEFICIALLY -------------------------------------- OWNED BY 8 SHARED VOTING POWER EACH 13,027,893 REPORTING -------------------------------------- PERSON 9 SOLE DISPOSITIVE POWER WITH None -------------------------------------- 10 SHARED DISPOSITIVE POWER 13,027,893 - -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 13,027,893 - -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES* [ ] - -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 28.3% - -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* IN - -------------------------------------------------------------------------------- Item 1. Security and Issuer. (a) Common Stock, $0.02 par value ("Shares") Cypress Bioscience, Inc. (the "Issuer") 4350 Executive Drive, Suite 325 San Diego, CA 92121 (619) 452-2323 Item 2. Identity and Background. Names of Persons Filing: (a) This statement is filed on behalf of Paramount Capital Asset Management, Inc. ("Paramount Capital"), Aries Domestic Fund, L.P. ("Aries Domestic"), Aries Master Fund, a Cayman Island exempted company ("Aries Fund") and Lindsay A. Rosenwald, M.D. ("Dr. Rosenwald" and collectively, "Reporting Parties"). The shares of Common Stock that may be deemed beneficially owned by Paramount Capital and Dr. Rosenwald include 197,858 shares held by Aries Domestic Fund II, L.P. ("Aries II"). Paramount Capital and Dr. Rosenwald disclaim membership in a group with Aries II, and Paramount Capital and Dr. Rosenwald disclaim beneficial ownership of the shares held by Aries II, except to the extent of their respective pecuniary interests though, if any. See attached Exhibit A which is a copy of their agreement in writing to file this statement on behalf of each of them. (b) Paramount Capital's, Aries Domestic's and Dr. Rosenwald's business address is 787 Seventh Avenue, 48th Floor, New York, New York, 10019. The business address for Aries Fund is c/o MeesPierson (Cayman) Limited, P.O. Box 2003, British American Centre, Phase 3, Dr. Roy's Drive, George Town, Grand Cayman. (c) Dr. Rosenwald is an investment banker, venture capitalist, fund manager and sole shareholder of Paramount Capital/1/, a Subchapter S corporation incorporated in Delaware. Paramount Capital is the General Partner of Aries Domestic/2/, a limited partnership incorporated in Delaware. Paramount Capital is the Investment Manager to Aries Fund/3/, a Cayman Islands exempted company. (d) Dr. Rosenwald, Paramount Capital, Aries Domestic and Aries Fund and their respective officers, directors, general partners, investment managers, or trustees have not, during the five years prior to the date hereof, been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors). (e) Dr. Rosenwald, Paramount Capital, Aries Domestic and Aries Fund and their respective officers, directors, general partners, investment managers, or trustees have not been, during the five years prior to the date hereof, parties to a civil proceeding of a judicial or administrative body of competent jurisdiction, as a result of which such person was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, Federal or State securities laws or finding any violation with respect to such laws. (f) Dr. Rosenwald is a citizen of the United States. - ---------------------- /1/ Please see attached Exhibit B indicating the executive officers and directors of Paramount Capital and providing information called for by Items 2-6 of this statement as to said officers and directors. Exhibit B is herein incorporated by reference. /2/ Please see attached Exhibit C indicating the general partner of Aries Domestic and the general partner's executive officers and directors and providing information called for by Items 2-6 of this statement as to said general partners, officers and directors. Exhibit C is herein incorporated by reference /3/ Please see attached Exhibit D indicating the investment manager of the Aries Fund and the investment manager's executive officers and directors and providing information called for by Items 2-6 of this statement as to said investment manager and officers and directors. Exhibit D is herein incorporated by reference. Item 3. Source and Amount of Funds or Other Consideration. Since the date of Amendment No. 3 to Schedule 13D ("Amendment No. 1") which was filed on June 21, 1999, Aries Domestic used its general funds to make certain open market acquisitions of the securities of the Issuer and the Aries Fund used its general funds to make certain open market acquisitions of the securities of the Issuer as more fully set forth in Item 5. Aries Domestic Fund II, L.P., a Delaware limited partnership for which Paramount Capital serves as general partner also used its general funds to make certain open market acquisitions of the securities of the Issuer as more fully set forth in Item 5. Item 4. Purpose of Transaction. The Reporting Parties acquired shares of Common Stock of the Issuer as an investment in the Issuer. Although the Reporting Parties have not formulated any definitive plans, they may from time to time acquire, or dispose of, Common Stock and/or other securities of the Issuer if and when they deem it appropriate. The Reporting Parties may formulate other purposes, plans or proposals relating to any of such securities of the Issuer to the extent deemed advisable in light of market conditions, investment policies and other factors. Except as indicated in this Schedule 13D, the Reporting Parties currently have no plans or proposals that relate to or would result in any of the matters described in subparagraphs (a) through (j) of Item 4 of Schedule 13D. Item 5. Interest in Securities of the Issuer. (a) As of August 17, 1999, Dr. Rosenwald and Paramount Capital, through acquisition of the shares by the Aries Fund and Aries Domestic, beneficially owned 13,027,893 shares or 28.3% of the Issuer's securities and Aries Domestic and the Aries Fund beneficially owned as follows: Amount Owned ------------ Aries Domestic 3,855,371 Shares Aries Fund 8,974,664 Shares (b) Dr. Rosenwald and Paramount Capital share the power to vote or to direct the vote, to dispose or to direct the disposition of those shares owned by each of Aries Domestic and Aries Fund. (c) The following purchases were made by Aries Domestic in the open market since the filing of Amendment No. 3: Date Amount Price Per Share ---- ------ --------------- 06/15/99 2,970 $ 3.272 06/16/99 2,970 $ 3.365 06/16/99 2,970 $ 3.318 06/17/99 2,970 $ 3.380 06/17/99 1,485 $ 3.469 06/18/99 4,455 $ 3.271 06/18/99 11,880 $ 3.100 06/18/99 7,425 $ 3.270 06/21/99 2,970 $ 3.156 06/21/99 3,861 $ 3.219 06/22/99 8,910 $ 3.300 06/22/99 1,480 $ 3.281 06/23/99 1,480 $ 3.225 06/23/99 145 $ 3.125 06/23/99 2,970 $ 3.250 06/24/99 2,970 $ 3.219 06/24/99 5,049 $ 3.195 06/24/99 1,200 $ 3.250 06/24/99 2,970 $ 3.125 06/25/99 8,910 $ 3.125 06/25/99 1,480 $ 3.125 06/25/99 5,940 $ 3.154 06/29/99 1,480 $ 3.094 06/29/99 1,480 $ 3.154 06/29/99 5,940 $ 3.185 06/30/99 1,450 $ 3.125 06/30/99 1,450 $ 3.248 06/30/99 10,150 $ 3.220 07/02/99 5,000 $ 3.123 07/06/99 5,000 $ 3.123 07/07/99 1,500 $ 3.091 07/08/99 3,000 $ 3.065 07/08/99 4,500 $ 3.090 07/09/99 10,000 $ 3.055 07/09/99 28,000 $ 3.040 07/09/99 5,000 $ 3.000 07/09/99 15,000 $ 3.031 07/09/99 5,000 $ 3.065 07/12/99 1,500 $ 3.000 07/12/99 1,500 $ 3.000 07/13/99 10,000 $ 2.984 07/13/99 25,000 $ 2.920 07/13/99 3,000 $ 3.000 07/19/99 5,000 $ 2.938 07/19/99 4,534 $ 3.000 07/20/99 1,493 $ 3.031 07/20/99 9,371 $ 3.023 07/20/99 1,493 $ 3.000 07/20/99 1,493 $ 2.982 07/21/99 1,493 $ 3.000 07/22/99 1,493 $ 2.875 07/23/99 2,986 $ 2.935 07/23/99 4,479 $ 2.875 07/26/99 1,493 $ 2.940 07/27/99 2,986 $ 2.935 07/28/99 1,493 $ 2.875 07/28/99 2,986 $ 2.938 07/28/99 2,986 $ 2.935 07/29/99 1,493 $ 2.774 07/29/99 8,958 $ 2.894 07/29/99 299 $ 2.719 07/30/99 5,972 $ 2.880 07/30/99 4,479 $ 2.896 08/02/99 1,480 $ 2.685 08/05/99 917 $ 2.750 08/05/99 1,480 $ 2.746 08/06/99 8,877 $ 2.677 08/06/99 5,918 $ 2.720 08/09/99 1,480 $ 2.630 08/09/99 1,480 $ 2.563 08/10/99 1,480 $ 2.613 08/10/99 2,959 $ 2.611 08/11/99 2,959 $ 2.547 08/11/99 2,959 $ 2.500 08/12/99 1,480 $ 2.790 08/12/99 1,480 $ 2.550 08/13/99 2,959 $ 2.664 08/13/99 1,480 $ 2.688 08/16/99 1,480 $ 2.750 08/16/99 1,480 $ 2.763 08/17/99 1,480 $ 2.810 The following purchases were made by the Aries Fund in the open market since the filing of Amendment No. 3: Date Amount Price Per Share ---- ------ --------------- 06/15/99 7,000 $ 3.272 06/16/99 7,000 $ 3.365 06/16/99 7,000 $ 3.318 06/17/99 7,000 $ 3.380 06/17/99 3,500 $ 3.469 06/18/99 10,500 $ 3.271 06/18/99 28,000 $ 3.100 06/18/99 17,500 $ 3.270 06/21/99 7,000 $ 3.156 06/21/99 9,100 $ 3.219 06/22/99 21,000 $ 3.300 06/22/99 3,500 $ 3.281 06/23/99 3,500 $ 3.225 06/23/99 350 $ 3.125 06/23/99 7,000 $ 3.250 06/24/99 11,900 $ 3.195 06/24/99 7,000 $ 3.125 06/24/99 7,000 $ 3.219 06/24/99 2,835 $ 3.250 06/25/99 21,000 $ 3.125 06/25/99 3,500 $ 3.125 06/25/99 14,000 $ 3.154 06/28/99 10,000 $ 3.216 06/28/99 5,000 $ 3.125 06/29/99 3,500 $ 3.094 06/29/99 3,500 $ 3.154 06/29/99 14,000 $ 3.185 06/30/99 3,500 $ 3.125 06/30/99 3,500 $ 3.248 06/30/99 24,500 $ 3.220 07/07/99 3,450 $ 3.091 07/08/99 6,900 $ 3.065 07/08/99 10,350 $ 3.090 07/12/99 3,450 $ 3.000 07/12/99 3,450 $ 2.934 07/13/99 7,000 $ 3.091 07/20/99 3,411 $ 3.031 07/20/99 617 $ 3.023 07/20/99 3,411 $ 3.000 07/20/99 3,411 $ 2.982 07/21/99 3,411 $ 3.000 07/22/99 3,411 $ 2.875 07/22/99 5,000 $ 2.938 07/23/99 6,882 $ 2.935 07/23/99 10,323 $ 2.875 07/26/99 3,441 $ 2.940 07/27/99 6,882 $ 2.938 07/27/99 6,882 $ 2.935 07/28/99 6,882 $ 2.935 07/28/99 3,441 $ 2.875 07/29/99 3,441 $ 2.774 07/29/99 20,646 $ 2.894 07/29/99 688 $ 2.719 07/30/99 13,764 $ 2.880 07/30/99 10,323 $ 2.896 08/02/99 3,440 $ 2.685 08/05/99 2,133 $ 2.750 08/05/99 3,440 $ 2.746 08/06/99 20,640 $ 2.677 06/06/99 13,760 $ 2.720 08/09/99 3,440 $ 2.630 08/09/99 3,440 $ 2.563 08/10/99 3,440 $ 2.613 08/10/99 6,880 $ 2.611 08/11/99 6,880 $ 2.547 08/11/99 6,880 $ 2.500 08/12/99 3,440 $ 2.790 08/12/99 3,440 $ 2.550 08/13/99 3,440 $ 2.664 08/13/99 6,880 $ 2.688 08/16/99 3,440 $ 2.750 08/16/99 3,440 $ 2.763 08/17/99 3,440 $ 2.810 The following purchases were made by the Aries Domestic Fund II, L.P. in the open market since the filing of Amendment No. 3: Date Amount Price Per Share ---- ------ --------------- 6/15/99 30 $ 3.272 6/16/99 30 $ 3.365 6/16/99 30 $ 3.318 6/17/99 30 $ 3.380 6/17/99 15 $ 3.469 6/18/99 45 $ 3.271 6/18/99 120 $ 3.100 6/18/99 75 $ 3.270 6/21/99 30 $ 3.156 6/21/99 39 $ 3.219 6/22/99 90 $ 3.300 6/22/99 20 $ 3.281 6/23/99 20 $ 3.225 6/23/99 5 $ 3.125 6/23/99 30 $ 3.250 6/24/99 51 $ 3.195 6/24/99 30 $ 3.125 6/24/99 30 $ 3.219 6/24/99 15 $ 3.250 6/25/99 90 $ 3.125 6/25/99 20 $ 3.125 6/25/99 60 $ 3.154 6/29/99 20 $ 3.094 6/29/99 20 $ 3.154 6/29/99 60 $ 3.185 6/30/99 50 $ 3.125 6/30/99 50 $ 3.248 6/30/99 350 $ 3.220 6/30/99 5,500 $ 3.094 07/01/99 5,000 $ 3.094 07/01/99 5,000 $ 3.245 07/07/99 50 $ 3.091 07/08/99 100 $ 3.065 07/08/99 150 $ 3.090 07/12/99 50 $ 3.000 07/12/99 50 $ 2.934 07/13/99 5,000 $ 2.938 07/14/99 5,000 $ 2.938 07/14/99 15,000 $ 2.988 07/15/99 5,000 $ 2.875 07/15/99 15,000 $ 2.823 07/15/99 20,000 $ 2.830 07/15/99 5,000 $ 3.000 07/16/99 5,000 $ 2.882 07/16/99 20,000 $ 2.950 07/19/99 5,000 $ 2.719 07/19/99 5,466 $ 3.000 07/20/99 66 $ 3.031 07/20/99 12 $ 3.023 07/20/99 66 $ 3.000 07/20/99 66 $ 2.982 07/21/99 66 $ 3.000 07/22/99 66 $ 2.875 07/23/99 132 $ 2.935 07/23/99 198 $ 2.875 07/26/99 66 $ 2.940 07/27/99 132 $ 2.935 07/27/99 132 $ 2.938 07/28/99 132 $ 2.935 07/28/99 66 $ 2.875 07/29/99 66 $ 2.774 07/29/99 396 $ 2.894 07/29/99 13 $ 2.719 07/30/99 264 $ 2.880 07/30/99 198 $ 2.896 08/02/99 81 $ 2.685 08/02/99 5,000 $ 2.813 08/03/99 10,000 $ 2.991 08/04/99 15,000 $ 2.708 08/04/99 5,000 $ 2.688 08/05/99 1,950 $ 2.750 08/05/99 80 $ 2.746 08/06/99 483 $ 2.677 08/06/99 322 $ 2.720 08/09/99 80 $ 2.630 08/09/99 80 $ 2.563 08/10/99 80 $ 2.613 08/10/99 161 $ 2.611 08/11/99 161 $ 2.547 08/11/99 161 $ 2.500 08/12/99 80 $ 2.790 08/12/99 80 $ 2.550 08/13/99 161 $ 2.664 08/13/99 80 $ 2.688 08/16/99 80 $ 2.750 08/16/99 80 $ 2.763 08/17/99 80 $ 2.810 Other than as set forth herein the Reporting Parties have not engaged in any transactions in the Common Stock of the Issuer since the last filing. (d) & (e) Not applicable. Item 6. Contracts, Arrangements, Understandings or Relationships with respect to Securities of the Issuer Paramount Capital is the investment manager of the Aries Fund and the General Partner of Aries Domestic and in such capacities has the authority to make certain investment decisions on behalf of such entities, including decisions relating to the securities of the Issuer. In connection with its investment management duties, Paramount Capital receives certain management fees and performance allocations from the Aries Fund and Aries Domestic. Dr. Rosenwald is the sole shareholder of Paramount Capital. Except as indicated in this 13D and exhibits, there is no contract, arrangement, understanding or relationship between the Reporting Parties and any other person, with respect to any securities of the Issuer. Item 7. Material to be Filed as Exhibits: Exhibit A - Copy of an Agreement between Dr. Rosenwald, Paramount Capital, Aries Domestic and Aries Fund to file this Statement on Schedule 13D on behalf of each of them. Exhibit B - List of executive officers and directors of Paramount Capital and information called for by Items 2-6 of this statement relating to said officers and directors. Exhibit C - List of executive officers and directors of Aries Domestic and information called for by Items 2-6 of this statement relating to said officers and directors. Exhibit D - List of executive officers and directors of Aries Fund and information called for by Items 2-6 of this statement relating to said officers and directors. SIGNATURES After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. PARAMOUNT CAPITAL ASSET MANAGEMENT, INC. Dated: August 19, 1999 New York, NY By /s/ Lindsay A. Rosenwald, M.D. --------------------------------- Lindsay A. Rosenwald, M.D. Chairman ARIES DOMESTIC FUND By Paramount Capital Asset Management, Inc. General Partner Dated: August 19, 1999 New York, NY By /s/ Lindsay A. Rosenwald, M.D. --------------------------------- Lindsay A. Rosenwald, M.D. Chairman THE ARIES MASTER FUND By Paramount Capital Asset Management, Inc. Investment Manager Dated: August 19, 1999 New York, NY By /s/ Lindsay A. Rosenwald, M.D. ------------------------------------ Lindsay A. Rosenwald, M.D. Chairman Dated: August 19, 1999 New York, NY By /s/ Lindsay A. Rosenwald, M.D. ------------------------------------- Lindsay A. Rosenwald, M.D. EXHIBIT A AGREEMENT JOINT FILING OF SCHEDULE 13D The undersigned hereby agrees to jointly prepare and file with regulatory authorities a Schedule 13D and any future amendments thereto reporting each of the undersigned's ownership of securities of Cypress Bioscience, Inc., and hereby affirm that such Schedule 13D is being filed on behalf of each of the undersigned. PARAMOUNT CAPITAL ASSET MANAGEMENT, INC., INC. Dated: August 19, 1999 New York, NY By /s/ Lindsay A. Rosenwald. M.D. ------------------------------------ Lindsay A. Rosenwald, M.D. Chairman ARIES DOMESTIC FUND, L.P. By Paramount Capital Asset Management, Inc. General Partner Dated: August 19, 1999 New York, NY By /s/ Lindsay A. Rosenwald M.D. ----------------------------------- Lindsay A. Rosenwald, M.D. Chairman THE ARIES MASTER FUND By Paramount Capital Asset Management, Inc. Investment Manager Dated: August 19, 1999 New York, NY By /s/ Lindsay A. Rosenwald, M.D. ---------------------------------- Lindsay A. Rosenwald, M.D. Chairman Dated: August 19, 1999 New York, NY By /s/ Lindsay A. Rosenwald, M.D. ----------------------------------- Lindsay A. Rosenwald, M.D. EXHIBIT B The name and principal occupation or employment, which in each instance is with Paramount Capital Asset Management, Inc. ("Paramount Capital") located at 787 Seventh Avenue, 48th Floor, New York, New York, 10019, of each executive officer and director of Paramount Capital is as follows: PRINCIPAL OCCUPATION NAME OR EMPLOYMENT ---- ------------- Lindsay A. Rosenwald, M.D. Chairman of the Board of Paramount Capital Asset Management, Inc., Paramount Capital Investments, LLC and Paramount Capital, Inc. Mark C. Rogers, M.D. President of Paramount Capital Asset Management, Inc., Paramount Capital Investments, LLC and Paramount Capital, Inc. Peter Morgan Kash Director of Paramount Capital Asset Management, Inc., Senior Managing Director, Paramount Capital, Inc. Dr. Yuichi Iwaki Director of Paramount Capital Asset Management, Inc., Professor, University of Southern California School of Medicine Item 2. During the five years prior to the date hereof, none of the above persons (to the best of Paramount Capital's knowledge) was convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors) or was a party to a civil proceeding of a judicial or administrative body of competent jurisdiction, as a result of which such person was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, Federal or State securities laws or finding any violation with respect to such laws. Items 3-6. Please refer to Items 3-6 herein reporting the beneficial ownership. EXHIBIT C The name and principal occupation or employment, which is located at 787 Seventh Avenue, 48th Floor, New York, New York, 10019, of the General Partner of Aries Domestic is as follows: PRINCIPAL OCCUPATION NAME OR EMPLOYMENT ---- ------------- Paramount Capital Asset Management, General Partner; Investment Manager Inc. Exhibit B is hereby incorporated by reference. Item 2. During the five years prior to the date hereof, the above person (to the best of Aries Domestic's knowledge) has not been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors) or was a party to a civil proceeding of a judicial or administrative body of competent jurisdiction, as a result of which such person was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, Federal or State securities laws or finding any violation with respect to such laws. Items 3-6. Please refer to Items 3-6 herein reporting the beneficial ownership. EXHIBIT D The name and principal occupation or employment, which in each instance is with The Aries Master Fund ("Aries Fund") located at 787 Seventh Avenue, 48th Floor, New York, New York, 10019, of each executive officer and director of Aries Trust is as follows: PRINCIPAL OCCUPATION NAME OR EMPLOYMENT ---- ------------- Paramount Capital Asset Management, Inc. Investment Manager MeesPierson (Cayman) Management Limited Administrator Exhibit B is hereby incorporated by reference. Item 2. During the five years prior to the date hereof, neither of the above persons (to the best of Aries Fund's knowledge) have been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors) or was a party to a civil proceeding of a judicial or administrative body of competent jurisdiction, as a result of which such person was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, Federal or State securities laws or finding any violation with respect to such laws. Items 3-6. Please refer to Items 3-6 herein reporting the beneficial ownership. -----END PRIVACY-ENHANCED MESSAGE-----